Its therapeutic programs aim at the identification, optimization and development of pioneering and innovative

  • Small molecule Wnt-inhibitors for use in the treatment of colorectal cancer

The Wnt signaling pathway is believed to be causally related to several pathological conditions, in particular colorectal cancer. Three novel and proprietary drug target regulating the activity of this pathway are in our possession and the Company¡¯s most advanced small molecule Wnt-inhibitors block the interaction between Bcl9/hLgs and beta-Catenin, the key regulatory protein in this physiological process.

  • Amyloid-beta (Abeta)-lowering small molecules for the therapy of Alzheimer¡¯s disease

Amyloidosis and the formation of amyloid (senile) plaques in the brain are believed to be causally related to the development and pathogenesis of Alzheimer¡¯s disease. Amyloid plaques primarily consist of aggregates of Aß42 (Abeta), a small and highly neurotoxic peptide. The Company has identified small molecules that have shown significant Abeta-lowering in the cerebrospinal fluid and cortices of treated animals.

¡¡


The Genetics Company offers highly selective ELISA test kits for the specific and quantitative measurement of human Amyloid ¦Â1-40 and ¦Â1-42 peptides. Our unique and innovative kits are tailor-made for the early and reliable diagnosis of Alzheimer¡¯s in patients thus supplementing current diagnostic methods as well as the monitoring of disease therapies in clinical trials and preclinical and laboratory research.

We currently offer three ELISA test kits which are available for detection of human Amyloid ¦Â1-40 and ¦Â1-42 peptides:

1. CE-Certified ELISA test for cerebrospinal fluid (CSF) with a detection range of 100-2000 pg/ml. Ideal for
   your clinical trials and for early stage patient diagnosis

2. Highly sensitive ELISA (hs ELISA) test with a detection range of 25-500 pg/ml. This test can be used with a
   variety of samples including cell culture supernatants and cell lysates. Ideal for preclinical and laboratory
   research.

3. Highly sensitive brain ELISA test  with a detection range of 25-500 pg/ml. This test was specifically
   developed for the quantification of human beta-Amyloid in neuronal tissue samples. Ideal for preclinical
   and laboratory reseach

ELISA Kits - Products

1. CSF-ELISA
2. High Sensitivity ELISA
3. Brain ELISA  NEW


Anti-human beta-Amyloid Antibodies

The Genetics Company provides a range of highly purified monoclonal antibodies and antibody conjugates most selectively and specifically recognizing beta-Amyloid peptides. Our monoclonal antibodies are ideal for use in Western blotting (WB), Immunohistochemistry (IHC) and ELISA testing, ensuring highly reproducible and optimal results.

All anti-human beta-Amyloid antibodies are available as:

  • purified IgGs (Clones WO-2, G2-10, G2-11 & G2-13)
  • biotin conjugates (Clones WO-2, G2-10 & G2-13)
  • peroxidase conjugates (Clones WO-2, G2-10 & G2-13)

Anti-human Tau Antibodies

Furthermore, The Genetics Company provides monoclonal antibodies for the highly sensitive and selective detection of Alzheimer¡¯s disease related isoforms of human Tau protein

Antibodies - Products

1. Human Beta-Amyloid
2. Human Tau
¡¡
¡¡
Home  :   Biz Opportunities  :  Useful Information  :  Related Website  :  About Us  :  Contact Us
Copyright ?2006. All Rights Reserved